OnXpansion: Automated, targeted expansion of patient tumor samples for clinical biomarker analysis and personalized treatment

Unmet Medical Need: At least 40% of biopsies may be inadequate (and thus must be repeated), delaying personalized care. Currently, increasing the biopsy sample’s size would require changing from a minimally invasive, outpatient procedure to a surgical procedure, causing increased costs, resource utilization and morbidity. The current practices to address these shortcomings—repeat biopsy, liquid biopsy and patient-derived xenografts—all have their own disadvantages

Envisioned Healthcare Product: A method and device for expanding scant patient samples into clinically useful quantities for diagnostic biomarker testing for personalized cancer treatments.