The Small Business Technology Transfer (STTR) is a program that expands funding opportunities in the federal innovation research and development (R&D) arena. Central to the program is expansion of the public/private sector partnership to include the joint venture opportunities for small businesses and nonprofit research institutions. The unique feature of the STTR program is the requirement for the small business to formally collaborate with a research institution in Phase I and Phase II. STTR's most important role is to bridge the gap between performance of basic science and commercialization of resulting innovations.

  • Each participating agency (e.g. NSF, DOE, NIH, and DOD) releases RFPs for their own topics
  • Phase I award = $150-$250K for feasibility studies and proof-of-concept experimentation
  • Phase II awards = upwards of $1 million over multiple years
  • Have to have completed a Phase I award in order to apply for Phase II
  • Phase II expands upon the initial Phase I results and further develops the concept, usually to the pilot stage
  • SBIR vs. STTR
  • Under STTR, business must perform at least 40% of the work and the research institution must perform at least 30%
  • Under SBIR, the research institution can complete up to 33% of the total effort for a Phase I, and up to 50% for Phase II

National Science Foundation (NSF)

NSF funds research and education in most fields of science and engineering. The BME program supports research in molecular, cellular, and tissue approaches for advanced biomanufacturing and neural engineering and brain mapping. Typical award size for this program is around $100,000 per year with allowance for $200,000 for collaborative projects with multiple investigators. 


Has to be devised from a technology that has received NSF funding within the past 6 years. Need an external mentor. Up to $200K in funding for proof-of-concept or to scale up a prototype


ELab NYC is a prestigious 6-month training and mentorship program for aspiring entrepreneurs in New York City’s life sciences and healthcare technology community. The Lab provides extensive support to graduate students of science, post-docs, early-career researchers and engineers interested in forming new biotech and health tech ventures.


Bio & Health Tech SBIR Impact NYC is a competitive one-on-one SBIR/STTR application assistance program for life sciences and healthcare technology ventures based in New York City. 

Digital Health Breakthrough Network offers rapid validation for early-stage health tech startups by enabling them to collaborate with NYC-based healthcare providers quickly and affordably. 

Bio & Health Tech Entrepreneurship Lab NYC is a prestigious six-month training and coaching program for aspiring entrepreneurs in the city’s life sciences and healthcare technology community.

National Institutes of Health (NIH) 

Depending on your specific area of interest, browse the specific NIH Institutes, Centers and Offices website, for recently cleared concepts or upcoming solicitations. This website presents key information, including the objectives and descriptions of future solicitations and a direct link to NIH staff contacts. The listing of potential future initiatives is meant to provide the earliest possible alert to potential applicants in order to maximize application preparation time. For a listing of NIH Institutes, Centers and Offices, go to and then search for recently cleared concepts..

Department of Defense (DoD)

The Defense Advanced Research Projects Agency (DARPA) is the central research and development organization for the DOD. It manages and directs selected basic and applied research and development projects for the DOD. 

New York State Department of Health

The New York State Department of Health is comprised of a number of offices that provide funding for research that will address healthcare issues affecting New Yorkers.

New York Stem Cell Science (NYSTEM)

NYSTEM was created for the purpose of administering grants for basic, applied, translational or other research and development activities, and facilitates the acquisition and development of specialized equipment, that will advance scientific discoveries in fields related to stem cell biology.

Fraunhofer Center for Manufacturing Innovation (CMI)

This facility provides product development assistance and manufacturing solutions to local and international industry, as well as University developed projects. It works with its clients to develop new technologies, improve current manufacturing operations and benchmark against the world’s best practices. Fraunhofer Institutes work with industry and universities to scale up cutting edge research into real working technologies on an industrial time table. Their engineering leads to the development of advanced machinery and processes for a variety of applications. These range from submicron precision assembly for the photonics, biotech and semiconductor industries, to high volume manufacture of consumer products.

American College of Sports Medicine

Research Grant program that will fund $5,000 for research related to sports medicine.

Aid for Cancer Research

Grants program from Cancer related projects, will not fund salaries.